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NDPH

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Sleep and a daily headache: breaking the loop.

Pain makes it hard to sleep, and poor sleep makes pain harder to bear. With a headache that never stops, that loop can feel permanent. Sleep is one of the few things you can work on yourself, and in chronic migraine, changing sleep habits has reduced headaches in trials.

Sleep and headache feed each other

In a Norwegian study that followed more than 15,000 headache-free adults for 11 years, those with insomnia at the start were 40% more likely to have developed headaches by the end. The link was strongest for chronic headache.51

There is little sleep research in NDPH specifically, but what exists points the same way. In 527 children and teenagers seen at a headache clinic, those with NDPH had more sleep disturbance than those with migraine. Across all the groups, worse sleep went with more disability, anxiety and low mood.52

What helped in trials

The trials were done in chronic migraine, not NDPH, so take them as a reasonable bet rather than proof.

The sleep rules from the trial

These are the instructions given in the 2007 trial:53

  1. Go to bed and get up at the same time every day, allowing about eight hours in bed.
  2. No television, reading or music in bed.
  3. Use a visualisation exercise to fall asleep more quickly.
  4. Eat your last meal at least four hours before bed, and drink little in the two hours before.
  5. No naps during the day.

Give it a few weeks. A bad night will still happen; the goal is to stop one bad night from turning into a bad pattern.

When it might be something else

A headache that is there when you wake up, with loud snoring, pauses in breathing that someone else has noticed, or heavy daytime sleepiness, can come from obstructive sleep apnoea. In the international classification, this headache is present on waking and usually goes within four hours.1 It is worth mentioning to your doctor, because a sleep study can diagnose it and treatment can help.

Melatonin

Melatonin has only been studied in migraine. One randomised trial found 3 mg at night worked better than placebo and about as well as amitriptyline, with fewer side effects;22 another found it no better than placebo.23 It is generally well tolerated, but ask your doctor or pharmacist first, especially if you take other medicines.

Medicines and sleep

Some headache preventives cause drowsiness, others can keep you awake, and painkillers taken late at night can affect sleep too. If a medicine seems to be changing your sleep, tell your doctor — often the time you take it can be changed. Don’t stop it on your own.

Note your sleep alongside your pain for a few weeks: the year calendar has a notes area, and the app includes sleep in its daily headache-risk estimate. Bring what you find to your next appointment, with the appointment planner.

References

Numbers in the text link to these sources. Where the evidence comes from migraine rather than NDPH, the text says so.

  1. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders, 3rd edition. Cephalalgia 2018;38(1):1-211. doi.org/10.1177/0333102417738202
  2. Gonçalves AL, Martini Ferreira A, Ribeiro RT, et al. Randomised clinical trial comparing melatonin 3 mg, amitriptyline 25 mg and placebo for migraine prevention. J Neurol Neurosurg Psychiatry 2016;87:1127-32. doi.org/10.1136/jnnp-2016-313458
  3. Alstadhaug KB, Odeh F, Salvesen R, Bekkelund SI. Prophylaxis of migraine with melatonin: a randomized controlled trial. Neurology 2010;75:1527-32. doi.org/10.1212/WNL.0b013e3181f9618c
  4. Ødegård SS, Sand T, Engstrøm M, Stovner LJ, et al. The long-term effect of insomnia on primary headaches: a prospective population-based cohort study (HUNT-2 and HUNT-3). Headache 2011;51:570-80. doi.org/10.1111/j.1526-4610.2011.01859.x
  5. Rabner J, Kaczynski KJ, Simons LE, LeBel A, et al. Pediatric headache and sleep disturbance: a comparison of diagnostic groups. Headache 2018;58:217-28. doi.org/10.1111/head.13207
  6. Calhoun AH, Ford S. Behavioral sleep modification may revert transformed migraine to episodic migraine. Headache 2007;47:1178-83. doi.org/10.1111/j.1526-4610.2007.00780.x
  7. Smitherman TA, Walters AB, Davis RE, Ambrose CE, et al. Randomized controlled pilot trial of behavioral insomnia treatment for chronic migraine with comorbid insomnia. Headache 2016;56:276-91. doi.org/10.1111/head.12760